Thus, the molecular docking evaluation of B. bowkeri crude extract revealed potential inhibitory activity against key enzymes implicated in hypercholesterolemia and inflammation, including cyclooxygenase (COX), hormone-sensitive lipase (HSL), and 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. The gene discussed is LIPE; the disease is familial hypercholesterolemia.