ARFIP2 and obesity due to melanocortin 4 receptor deficiency: When analyzing Adi-poR1 expression in the liver, two-way ANOVA revealed significance of OEA-DS insertion (F (1, 8) = 7.640; p = 0.0245), as well as factor interactions (F (1, 8) = 12.25; p = 0.0081), while serum ANOVA revealed the significance of obesity factors (F (1, 8) = 7.895; p = 0.0229) and OEA-DS administration (F (1, 8) = 17.50; p = 0.0031).