Monocyte activation with palmitate for 18 h before infection (referred to as priming) with different SARS‐CoV‐2 variants (B1, Delta, Omicron) led to an increased viral load and elevated gene expression of IL‐6 and IL‐1β in all variants tested (Figure 1D–F and Supporting Information: Figure 1B–H). Here, IL1B is linked to infection.