Studying the expression and functional identification of genes and proteins related to the VEGF signalling pathway in echinococcosis can help understand the progression of HAE at the cellular and molecular levels, reveal the relationship between Echinococcus and the human body in various types of pathological processes, and provide a relevant scientific basis for the prevention and treatment, prognosis, and other aspects of HAE. This evidence concerns the gene VEGFA and hereditary angioedema.