FGFR3 and central nervous system cancer: Firstly, we included the Kaplan-Meier survival curves for glioma patients with high and low FGFR3 expression from TCGA database, we can observe that glioma patients with higher FGFR3 expression always have poor prognosis than those with lower FGFR3 expression (Figure 1A) (p = 0.008).