The expression profiles of the galectin gene family, especially galectin-1 and galectin-3, were found to differ between primary and metastatic papillary thyroid carcinoma in tissue samples of benign and malignant thyroid nodules (13); Based on the proteome of thyroid tissue samples, metastasis related markers were recorded (14, 15). The gene discussed is LGALS3; the disease is differentiated thyroid carcinoma.