CPS1 and obstructive sleep apnea syndrome: In addition, it has been suggested that overexpressed lncRNA CPS1-IT can slow down the progression of pulmonary hypertension in patients with OSAHS by modulating the transcriptional activity of hypoxia-inducible factor 1 (HIF1) to reduce the expression of interleukin-1β (IL-1β) (Zhang et al., 2019).