Considering the importance of GABA-mediated neurotransmission, regulation of intracellular chloride concentration by cation-chloride cotransporter, specifically KCC2, in epilepsy and the beneficial effects of KD in this disease, the results presented in this study include data on body weight, glucose and β-hydroxybutyrate concentration, as well as ADD, latency and duration of stages in rats fed with a KD under the amygdala kindling model. Here, SLC12A5 is linked to epilepsy.