IL6 and allergic disease: In addition, IL-10 can inhibit activated monocytes from secreting interleukin-1 (IL-1) and interleukin-6 (IL-6) (47), suppress the release of TNF-α by macrophages (48), and inhibit the activation of mast cells and the secretion of their cytokines (49, 50), thereby participating in the regulation of allergic reactions (40, 51).