Among the top 10 pathways identified through KEGG pathway analysis, pathways in cancer, proteoglycans in cancer, the PI3K-Akt signaling pathway, cytokine–cytokine receptor interaction, focal adhesion, the mitogen-activated protein kinases (MAPK) signaling pathway, the chemokine signaling pathway, and endocytosis may be involved in the tumorigenesis and pathogenesis of LUAD (Figures 3C, D). This evidence concerns the gene WNK2 and cancer.