Among the top 10 pathways identified through KEGG pathway analysis, pathways in cancer, proteoglycans in cancer, the PI3K-Akt signaling pathway, cytokine–cytokine receptor interaction, focal adhesion, the mitogen-activated protein kinases (MAPK) signaling pathway, the chemokine signaling pathway, and endocytosis may be involved in the tumorigenesis and pathogenesis of LUAD (Figures 3C, D). The gene discussed is AKT1; the disease is cancer.