CD8A and neoplasm: investigated the dynamic changes in the immune microenvironment of tumor-draining lymph nodes (TdLN) after MWA in an LLC murine model and reported a significant increase in the frequency of CD4+ T cells from day 1 to day 8 and a significant decrease in CD8+ T cell frequency on days 2 and 4 after MWA; however, no significant changes were observed on days 1 and 8 (74).