reported that TAMs modified the expression of miR-92a-2-5p in exosomes, which reduced AR expression and subsequently regulated the pleckstrin homology domain leucine-rich repeat protein phosphatases (PHLPP)/p-AKT/β-catenin signaling pathway, leading to enhanced the invasive capabilities of HCC cells in preclinical models (122). The gene discussed is AR; the disease is hepatocellular carcinoma.