To this end, this study aims to select a panel of potential inflammatory factors, including ferroptosis proteins (ACSL4, GPX4, and PTGS2), chemokines, cytokines, and collectin-11(CL-11) and investigate the clinical value of these proteins in the diagnosis and prognosis of sepsis, as well as predicting mortality risk in a newly established cohort of sepsis patients. This evidence concerns the gene ACSL4 and Sepsis.