T1DM: type 1 diabetes mellitus; T2DM: type 2 diabetes mellitus; PCSK9: proprotein convertase subtilisin/kexin type 9; LDL-C: low-density lipoprotein-cholesterol; HDL-C: high-density lipoprotein-cholesterol; Apo-B: apolipoprotein B. Here, APOB is linked to type 1 diabetes mellitus.