Fibrates are a class of medications used to treat dyslipidemia by activating the transcription factors peroxisome proliferator-activated receptors (PPARs) to reduce the level of TGs, triglyceride-rich lipoprotein cholesterol (TRL-C), and Lp(a) by stimulating fatty acid oxidation and increasing lipoprotein lipase (LPL) synthesis [30]. The gene discussed is LPL; the disease is metabolic syndrome.