Similarly, the proportion of EGFR+ tumor cells had a predictive AUC of 90.1% for EGFR amplification, with the best cutoff point at 14.3%, and the proportion of CDKN2A+ tumor cells had a predictive AUC of 79.4% for CDKN2A deletions with the best cutoff point of 0.5%. The gene discussed is CDKN2A; the disease is neoplasm.