In a large-scale prospective cohort study that took place in the Netherlands between 2009 and 2014 (104), with 5,825 participants included (mean age 69.5 ± 9.1 years, 49.2% men), liver stiffness is significantly associated with prevalent AF (OR 1.09 per kPa, 95% CI: 1.03–1.16, p = −0.002) using logistic regression adjusting for age, sex, alcohol consumption, smoking, education level, prevalent HF, prevalent cardiac heart disease and the individual component of metabolic syndrome, spleen size and inferior vena cava diameter and alanine aminotransferase (ALT). This evidence concerns the gene GPT and atrial fibrillation.