The results demonstrated that after the establishment of the DN model, indicators of kidney function, including serum creatinine (SCr), albumin (Alb), and 24-hour urinary albumin (24h-UAlb), were significantly elevated, and there were increased fasting blood glucose (FBG), total cholesterol (TC), and triglycerides (TG) levels. Here, ALB is linked to liver dysplastic nodule.