UGT2B28 and arthritic joint disease: For UGT2B28 KO females, several free fatty acids and the acyl carnitines octanoylcarnitine and decanoylcarnitine that were less abundant only in females were all linked to a reduced risk of cardiovascular diseases, whereas 3-hydroxy derivatives of decanoylcarnitine were associated with an increased risk of arthritis (Fig. 6E, F).