UGT2B17 and Familial prostate cancer: Despite the prevalence of these gene KOs in the population and the increasing number of diseases that have been linked to the complete deficiency of either enzyme in several small studies [21–24, 26, 27, 29, 46], research to date has predominantly focused on the association between UGT2B17 and prostate cancer [19, 20, 24], with limited reports on UGT2B28 [24].