DGAT2 and morbid obesity: In addition, we observed an upregulation of 10–30-fold for SCD, LIPIN1, and DGAT2 genes in low B12 primary Sc adipocytes derived from subjects with overweight and an increase of 20-fold for DGAT2 from subjects with morbid obesity (Fig. 1C, i–vi, p < 0.05).