BACH1 is involved in promoting metastasis by upregulating pro-metastatic genes such as HK2, GAPDH, CXCR4, MMP1, MMP13, and VEGF, and promotes the metastasis of cancer cells in vitro and in vivo (Liang et al, 2012; Lignitto et al, 2019; Wiel et al, 2019). This evidence concerns the gene BACH1 and cancer.