Among the top 30 proteins with highest variance were 12 immunoglobulins (CV between 22.0% and 89.2%), 4 hemolysis-related proteins (CV between 26.9% and 54.5%) as well as the hormone transporters transcortin (SERPINA6, CV = 48.3%) and sex hormone binding globulin (SHBG, CV = 123.3%; see Supplementary Table S4). The gene discussed is SHBG; the disease is hemolysis.