BRD9 and posterior cortical atrophy: To determine the functional role of BRD9 in the proliferation capacity of the established CRPC cells, colony formation (Fig. 1E), Cell Counting Kit-8 (CCK-8) (Fig. 1F) and EdU (Fig. 1I) assays were conducted, and the results confirmed that BRD9 overexpression promoted the growth of PCa cells under both normal and hormone-free conditions.