FGFR2 and Apert syndrome: The patient had a c.755 C > G (p.Ser252 Trp) Ser252 Trp pathogenic variant in FGFR2. Another study also reported a young girl with early-onset low-grade papillary cancer and a c.758 C > G (p.Pro253 Arg) Pro253 Arg FGFR2 pathogenic variant associated with Apert syndrome [41].