In an exploratory analysis of 68 IDHwt GBM patients with MGMT data, unmethylated cases (n = 45) had a mean PFS of 254 days (8.4 months; 95% CI: 5.9–10.8) and median 215 days (7.1 months; IQR: 3.2–10.1). The gene discussed is MGMT; the disease is glioblastoma.