F11 and hyperinsulinemic hypoglycemia, familial, 4: To dissect roles of fibrin depositions versus other pathways transgenic mice with nonpolymerizable fibrin (Hur et al., 2024) or analysis of cohorts of individuals with severe FXII deficiency (e.g., <1%) or patients on FXII(a)/FXI(a) inhibitors may provide valuable insights in future studies.