Studies have established the link between EMT and drug resistance particularly multidrug resistance phenotype due to the enhancement of cancer survival and upregulation of drug resistance genes such as drug transporters (ABCB1A, ABCB1B, and ABCC1), cytochrome P450s, and aldehyde dehydrogenase (ALDHs) (95, 107). Here, ABCC1 is linked to cancer.