The results are as follows: SLC14A1 (AUC 0.862), ARHGEF38 (AUC 0.817), NEFH (AUC 0.805), MSMB (AUC 0.784), KRT23 (AUC 0.728), KRT15 (AUC 0.824), all candidate genes have a high diagnostic value for PCa (Figure 5A). The gene discussed is ARHGEF38; the disease is posterior cortical atrophy.