Furthermore, the SLC14A1 gene is also considered a novel tumor suppressor for urothelial carcinoma, and in PCa, the downregulation of its expression promotes tumor progression by activating the CDK1/CCNB1 and mTOR pathways and is closely associated with biochemical recurrence (BCR) of PCa (32–34). Here, SLC14A1 is linked to posterior cortical atrophy.