ANG and neoplasm: Although the abnormal expression of single-class ANG have been shown to play an important role in promoting tumor angiogenesis and accelerating tumor progression, the study of clusters of several classes of ANG and their ligands and receptors together on the mechanism of tumor action is still waiting to be discovered by scholars (132, 133).The role of anti-tumor angiogenesis in cardiovascular disease The effect of anti-tumor angiogenesis on blood pressure in patients with cardiovascular disease needs to be studied.