A 41-year-old female with a 20-year history of SLE, recently diagnosed with stage IV diffuse large B-cell lymphoma, who received BCMA-CD19 compound CAR-T cells, exhibited reductions in nuclear, cytoplasmic, and granular ANA and total immunoglobulin levels, achieving remission of both SLE and lymphoma (97). This evidence concerns the gene CD19 and lymphoma.