The results demonstrated significant positive correlations between the expression levels of ARIH2 and CX3CR1 (r=0.418, P<0.001), CCL28 (r=0.363, P<0.001), CCR4 (r=0.312, P<0.001), CCR1 (r=0.289, P<0.001), CXCL3 (r=0.274, P<0.001) and CXCL8 (r=0.266, P<0.001) in HCC. This evidence concerns the gene CCR4 and hepatocellular carcinoma.