FAP and neoplasm: Research reports have indicated that engineered exosome-like nanovesicles (eNVs-FAP) can effectively decrease the proportion of immunosuppressive cells – encompassing M2-like tumor-associated macrophages (M2-TAMs), myeloid-derived suppressor cells (MDSCs), and Tregs – within the tumor microenvironment (TME), thereby promoting tumor ferroptosis (64).