We generated from this atlas a CD4+ T cell sub-atlas comprising scRNA-seq data for 119,960 CD4+ T cells from 64 treatment-naïve patients and 10 healthy donors, including colorectal cancer (CRC) (42), intrahepatic cholangiocarcinoma (CHOL) and hepatocellular carcinoma (HCC) (43), head and neck squamous cell carcinoma (HNSCC) (44), non-small cell lung cancer (NSCLC) (42), pancreatic ductal adenocarcinoma (PDAC) (45), renal cell carcinoma (RCC) (42, 46) and uterine corpus endometrial carcinoma (UCEC) (42) (Supplementary Figure S5A). Here, CD4 is linked to non-small cell lung carcinoma.