In ALK-negative IMT, ROS1 and NTRK3 gene rearrangements are the most common mutations, occurring in 5%–15% of cases, while RET and PDGFRB rearrangements are relatively rare (Takahashi et al., 2018; Huang et al., 2022; Yamamoto et al., 2016; Cheek et al., 2020; Comandini et al., 2021). Here, NTRK3 is linked to inflammatory myofibroblastic tumor.