Crizotinib, a tyrosine kinase inhibitor targeting ALK, MET, ROS1, and RON, is recommended by the National Comprehensive Cancer Network (NCCN) as a treatment option for ALK-positive IMT (Von Mehren et al., 2022; Trahair et al., 2019; Hunt et al., 2023). The gene discussed is MST1R; the disease is inflammatory myofibroblastic tumor.