For example, we accurately predict both cooperative interactions (FOS-JUN, FOS-FOSL2) regulating IL6 in granulocytes [inflammatory white blood cells (WBCs) that respond to infection] and monocytes (type of WBC that differentiates into macrophages or dendritic cells), as well as three out of five antagonistic PPIs regulating IL1B in Dn4 thymocytes (precursors of T-cells in the thymus). The gene discussed is JUN; the disease is infection.