According to Table 5 and Figure 1, after adjusting for various factors such as stroke type, treatment modality, stroke type, therapeutic modaliyies, vascular disease, SBP, HR, LDL-C, HDL-C, CREA, FIB, D-dimer, NT-proBNP, LVEF, admission to NIHSS, ESRS, and pre-stroke CHA2DS2-VASC-60 score, a significant association exists between the SII and in-hospital mortality risk. Here, NPPB is linked to Stroke.