INS and Glucose intolerance: Regarding adults, HGH has other described functions, including increasing lipolysis and lipid oxidation, which leads to mobilization of stored triglycerides, stimulation of protein synthesis that includes skeletal muscle anabolism, antagonism of insulin action that leads to glucose intolerance, and decrease of phosphate, water, and sodium renal excretion (Chikani and Ho, 2013; Ho et al., 2023).