FKBP1A and Parkinson disease: Studies have demonstrated that FKBP12 inhibition alone significantly contributes to neuroprotection in PD models (Steiner et al., 1997; Costantini et al., 1998; Tanaka and Ogawa, 2004; Gerard et al., 2010) and plays a role in α-syn pathobiology by preventing its aggregation (Gerard et al., 2006; Gerard et al., 2008).