The log2FC of LRRN3 were –0.606 (P = 0.0277) and –0.401 (P = 0.0002), and of TUBB2A were –0.639 (P = 0.0159) and –0.489 (P = 0.0053), respectively in the substantia nigra and blood of PD (Figure 6B). Here, TUBB2A is linked to Parkinson disease.