CHEK2 and breast cancer: It was found that 59 patients (19%) (Figure 1, Table 2) carried a deleterious germline variant, classified as pathogenic or probably pathogenic, in genes associated with hereditary cancer that could be involved in the development of breast cancer: 10 in BRCA1, 8 in BRCA2, 7 in ATM, 3 in CHEK2, 3 in TP53, 4 in MUTYH, 3 in FANCA and 4 in FANCM, among others.