ANK2 and myotonic dystrophy type 1: Our differential AS analysis revealed 0.3% (n = 306) mis-spliced events in 2% (n = 257) of analyzed genes (Fig. 6b and Extended Data Fig. 6a) with 15 mis-spliced AS events overlapping between DM1 and ASD (OR = 3.5, P = 5.7 × 10−5, Fisher’s exact test), including ANK2 miE (Fig. 6c).