The depletion of KDM4C (shKDM4C#1 or #2) significantly reduced their wound-healing capacity (Fig. S2A‒C), metastatic activity in the zebrafish xenotransplantation assay (Fig. S2D, E), and tumor growth in the mouse xenograft model (Fig. S2F, G). Here, KDM4C is linked to neoplasm.