AFP and hepatocellular carcinoma: Clinicians use the lens culinary agglutinin-reactive fraction of fetoprotein subtype as a diagnostic tool because this protein product originates from malignant hepatocytes exclusively.[10] The evaluation of AFP-L3% for detecting early HCC was absent from the previously conducted study which demonstrated a low pooled sensitivity of 0.483 at HCC diagnosis.[11] The main goal of this research was to examine HCC patient related elements impacting AFP-L3 levels and assess its use as a tool for detecting HCC at an early stage.