The CASP1 gene encodes caspase-1, which plays a significant role in inflammatory processes.[32] CASP1 is a well-known gene involved in pyroptosis, and metabolites of benzene have been found to trigger cell death through the activation of the Aim2/CASP1 pathway.[33] It has been established that cell pyroptosis significantly contributes to the activation of hemostasis in the context of sepsis.[34] Survival curve analysis revealed that increased expression of CASP1 in groups with better sepsis prognosis led to higher survival rates. The gene discussed is AIM2; the disease is Sepsis.