Thus, it’s possible that miR-191-5p may promote EMT of LECs by inhibiting KLF6. It’s been confirmed that exosome-transmitted miR-335-5p facilitates EMT of colorectal cancer cells via direct targeting of the specific region of the 3’ UTR of RAS p21 protein activator 1 (RASA1). Here, KLF6 is linked to colorectal cancer.