The enriched WIKI pathways of the 428 genes included ‘nonalcoholic fatty liver disease’, ‘mitochondrial complex I assembly model OXPHOS system’ and ‘oxidative phosphorylation’ (Figure 3(C)); as well as the enriched KEGG pathways contained ‘cAMP signaling pathway’, ‘pathways of neurodegeneration’, ‘nonalcoholic fatty liver disease’, ‘neurotrophin signaling pathway’, ‘thermogenesis’ and ‘oxidative phosphorylation’ (Figure 3(D)). The gene discussed is BDNF; the disease is metabolic dysfunction-associated steatotic liver disease.