In contrast, other invasive breast cancer cell lines, such as MDA-MB-231 cells, exhibited opposing responses to TRPV4 inhibition and activation, highlighting the heterogeneity of TRPV4 roles in invasive cancer progression (Lee et al., 2017; Prevarskaya et al., 2010; Bai et al., 2023). This evidence concerns the gene TRPV4 and breast carcinoma.