In hepatocellular carcinoma (HCC), TuBG1 overexpression was linked to poor prognosis, and its silencing led to increased ATR, p-P53, and apoptosis-related protein expression, reducing proliferation by M4344 (16). In ovarian cancer, SLFN11 downregulation contributed to cisplatin resistance, which was reversible by HDAC inhibition. This evidence concerns the gene HDAC9 and hepatocellular carcinoma.