PTPN1 and type 2 diabetes mellitus: In the management of type 2 diabetes mellitus (T2DM), severalmolecular targets have been identified as key therapeutic focuses,including α-glucosidase, dipeptidyl peptidase-4 (DPP-4), peroxisomeproliferator-activated receptor gamma (PPARγ), and protein tyrosinephosphatase 1B (PTP1B).5,6 These targets represent promisingavenues for the development of more effective treatments aimed ataddressing the global burden of diabetes and its complications.