Lipid-associated macrophages in the tumor-adipose microenvironment show high expression levels of genes involved in lipid metabolism (FABP3–5, LPL (lipoprotein lipase), and LIPA (lipase A)) and some lipid receptors (LGALS3 (lectin, galactoside-binding, soluble 1) and TREM2 (triggering receptor expressed on myeloid cells 2)).75 The gene discussed is LPL; the disease is neoplasm.