FGFR3 and achondroplasia: Decoy receptors against FGFR3 (soluble FGFR3, sFGFR3) containing mainly FGFR3 extracellular domain have been proven to compete with FGFR3 binding to endogenous FGF ligands, leading to decreased mortality and improved skeletal growth of ACH mice through functionally regulating chondrogenesis.106